Chromatography | MillennialScientific

News and Events

Sep 20

Milestone Alert: NanoPak-C Analytical Grade Media Successfully Passes Beta Testing Milestone

Millennial Scientific is pleased to announce a major achievement in our product development: the successful completion of the beta...

Sep 17

Chinese Patent Office Issues Notice of Allowance for Millennial Scientific’s Technology

Millennial Scientific is pleased to report that the Chinese Patent Office has issued the Company a Notice of Allowance concerning its...

Sep 13

Role of Flash Chromatography in Peptide Purification

Flash chromatography is a valuable tool in peptide purification workflows, especially as a pre-purification or cleanup step.

Aug 30

A Brief Primer on Hydrophobic Interaction Chromatography

This blog provides an easy-to-understand overview of hydrophobic interaction chromatography. Part of our separation science primer series.

Aug 1

The Impact of Composition, Aggregation, and Solubility on Glucagon-like peptide-1 Purification

pH-dependent aggregation behavior of peptides. In a previous blog post, we delved into the complex issue of peptide and protein...

Jul 29

Understanding Peptide and Protein Aggregation: A Guide to Terminologies, Implications, Factors, and the Role of Liquid Chromatography

The aggregation or clumping of peptides and proteins is a crucial phenomenon in biology , influenced by various factors [1]....

Jul 25

What are Flash Columns?

This post is part of our separation science primer series which provides an easy-to-understand overview of key topics in Flash...

Jul 12

Analyzing Bovine Serum Albumin (BSA) with NanoPak-C All Carbon HPLC Columns

NanoPak-C All Carbon media has adjustable pore size and surface area that is suitable for separating proteins in reverse phase. We demonstra

Jul 5

Understanding Ozempic, Wegovy, and Other GLP-1 Therapeutic Peptides: Background, Composition, and Manufacturing

Image adapted from [1]. Ozempic, Weight Loss, and GLP-1 Therapy Ozempic is a once-weekly injection first approved by the Food and Drug...

Jun 26

Simultaneous Determination of Insulin Aspart and its Phenolic Preservatives Using NanoPak-C All Carbon HPLC Columns

We have published an application note that presents a reliable and quick method using NanoPak- C All carbon columns for simultaneously...

Jun 17

Breaking Down the Key Differences: NanoPak-C All Carbon vs. Porous Graphitic Carbon-Based Stationary Phase Materials

In our previous blog, we explained the differences between NanoPak-C All Carbon microbeads and alkyl bonded silica. In this blog, we...

Jun 5

Separation of Semaglutide and Liraglutide: An Optimized Method Using NanoPak-C All Carbon Microbeads

We have published an application note that presents an optimized method for HPLC separation of semaglutide and liraglutide. This method...

May 30

Robust Solid Phase Extraction of Pesticides from Small or Limited Volume Environmental Samples

The constant monitoring of pesticides is imperative due to their potential environmental harm. These chemicals, including insecticides,...

May 24

How Does Peptide Manufacturing Affect the Environment?

Peptides are considered “medium molecules.” They typically consist of 2-50 amino acids, and their size is measured in molecular weights...

May 1

Demystifying Oligonucleotide Separation

Oligonucleotides are tiny fragments of DNA or RNA. Our genetic information is stored in DNA and RNA. These molecules are also known as...

Mar 29

Workflow for NanoPak-C All Carbon SPE of Trace Organochlorine Pesticides from Small Volume Complex Biological Samples

Mar 22

Carbon’s role in Reversed-Phase Liquid Chromatography Retention and Selectivity

The Basics The most widely used mode of chromatography is Reversed-Phase Liquid Chromatography (RPLC). Accounting for more than 90% of...

Feb 26

Championing Sustainability: How Millennial Scientific Supports the SDGs

Climate change & sustainability initiatives are significant drivers that are reshaping industries. Advanced materials and manufacturing,...

Feb 24

Solving New and Challenging Separations: Breaking Down Our Strategy

Our approach solves new and diverse separation challenges by: Moving away from one-shoe-fit-all and piecemeal solutions. Offering...

Feb 16

NanoPak-C All Carbon HPLC Capillary Columns for Proteomics & Other Biologics

Millennial Scientific is pleased to introduce NanoPak-C All Carbon capillary columns (less than 500 µm internal diameter (ID)) for...